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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM2 All Species: 24.24
Human Site: S850 Identified Species: 44.44
UniProt: Q14416 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14416 NP_000830.2 872 95568 S850 S S S L G Q G S G S Q F V P T
Chimpanzee Pan troglodytes A3QNZ8 839 95029 C812 L G Y F G P K C Y M I L F Y P
Rhesus Macaque Macaca mulatta A3QP01 839 95041 C812 L G Y F G P K C Y M I L F Y P
Dog Lupus familis XP_541867 872 95696 S850 S S S L G Q G S G S Q F V P T
Cat Felis silvestris
Mouse Mus musculus Q14BI2 872 95869 S850 S A N L G Q G S G S Q L V P T
Rat Rattus norvegicus P31421 872 95755 S850 S A N L G Q G S G S Q F V P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518731 870 95758 S848 G S S L S H G S G S Q F V P T
Chicken Gallus gallus XP_416842 879 98936 S857 G T T Y S Q S S A S M Y V P T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 T840 A E N I K G L T G T E P Q F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 T912 T S S G Y S R T H A P G T S A
Honey Bee Apis mellifera NP_001011624 933 103448 A901 E S M P L Q S A L T A A V Q T
Nematode Worm Caenorhab. elegans Q09630 999 113258 N967 A N S I D E P N Q Y T A L L T
Sea Urchin Strong. purpuratus XP_784936 1474 165598 Y1438 E V N N H N L Y N S G S V Q R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.6 27.6 98.1 N.A. 97.4 97.8 N.A. 88.3 67.9 N.A. 25.5 N.A. 45.7 47 39.9 32.2
Protein Similarity: 100 46.3 46.3 98.9 N.A. 98.5 98.7 N.A. 92.7 82.2 N.A. 43.8 N.A. 61.7 63.3 55.6 43.4
P-Site Identity: 100 6.6 6.6 100 N.A. 80 86.6 N.A. 80 40 N.A. 6.6 N.A. 13.3 26.6 13.3 13.3
P-Site Similarity: 100 6.6 6.6 100 N.A. 93.3 100 N.A. 80 60 N.A. 46.6 N.A. 33.3 40 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 16 0 0 0 0 0 8 8 8 8 16 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 16 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 16 0 0 0 0 0 0 0 31 16 8 0 % F
% Gly: 16 16 0 8 47 8 39 0 47 0 8 8 0 0 0 % G
% His: 0 0 0 0 8 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 16 0 0 0 0 0 0 16 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 16 0 0 0 0 0 0 0 8 % K
% Leu: 16 0 0 39 8 0 16 0 8 0 0 24 8 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 16 8 0 0 0 0 % M
% Asn: 0 8 31 8 0 8 0 8 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 16 8 0 0 0 8 8 0 47 16 % P
% Gln: 0 0 0 0 0 47 0 0 8 0 39 0 8 16 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 31 39 39 0 16 8 16 47 0 54 0 8 0 8 0 % S
% Thr: 8 8 8 0 0 0 0 16 0 16 8 0 8 0 62 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 62 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 8 8 0 0 8 16 8 0 8 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _